The Relationship Diremption: Break it off, Shake hands, Walk away
Sheldon: I’ve devoted the prime of my life to string theory, and its quest for compactification of interdimensions, I got nothing to show for it and I feel like a fool.
Penny: Ok I get it, […] I know what it’s like to put your heart and soul into something and get nothing out of it. […] Your problem seems like a relationship and I know what it’s like to be in one that’ll never turn up the way you want.
Sheldon: So, what do you do?
Penny: You have to have the courage to end the relationship, you know, break it off, shake hands, walk away…
Sheldon: I don’t know if I can do that…
Penny: I know it’s hard honey but in the end, that’s how you grow.